Being a part of DundeeChest is about pushing forwards, making changes, and being part of a great team here in Dundee. Over recent years we’ve published a number of pieces of independent research, presented posters and oral presentations at national and international meetings, and even won the occasional award. Here s a summary of some of the achievements of the department in recent times:
Faculty of Medical Educators Awards 2010. Nominated: Dr Tom Fardon. Award ceremony March 17th 2010.
Ralph Noble Prize from Cambridge University, for best Clinical Research doctorate academic year 2008-2009: Dr Tom Fardon
Proposed changes to management of lower respiratory tract infections in response to the Clostridium difficile epidemic: James D. Chalmers; Mudher Al-Khairalla; Philip M. Short; Tom C. Fardon; John H. Winter
Journal of Antimicrobial Chemotherapy 2010; doi: 10.1093/jac/dkq038
200 CXR Cases – An illustrated guide to CXRs for junior doctors and medical students. Written by Dr Mudher Al-Khairalla, Dr James Chalmers and Dr Tom Fardon. Available from Amazon
Risk factors for complicated parapneumonic effusion and empyema on presentation to hospital with community-acquired pneumonia: J D Chalmers, A Singanayagam, M P Murray, C Scally, A Fawzi, A T Hill Thorax 2009;64:592–597. doi:10.1136/thx.2008.105080
Faculty of Medical Educators Awards 2008. Winners: Dr James Chalmers and Dr Tom Fardon. Nominated: Dr Mudher Al-Khairalla
Recent publications from the Asthma and Allergy Research Unit in Dundee:
1: Clearie KL, Williamson PA, Vaidyanathan S, Short P, Goudie A, Burns P, Hopkinson P, Meldrum K, Howaniec L, Lipworth BJ. Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers. Clin Exp Allergy. 2010 Mar 1. [Epub ahead of print] PubMed PMID: 20214665.
2: Basu K, Nair A, Williamson PA, Mukhopadhyay S, Lipworth BJ. Airway and systemic effects of soluble and suspension formulations of nebulized budesonide in asthmatic children. Ann Allergy Asthma Immunol. 2009 Nov;103(5):436-41. PubMed PMID: 19927544.
3: Barnes ML, Vaidyanathan S, Williamson PA, Lipworth BJ. The minimal clinically important difference in allergic rhinitis. Clin Exp Allergy. 2010 Feb;40(2):242-50. Epub 2009 Nov 5. PubMed PMID: 19895590.
4: Lipworth BJ, Williamson PA. Think the impossible: beta-blockers for treating asthma. Clin Sci (Lond). 2009 Oct 12;118(2):115-20. PubMed PMID: 19807697.
5: Nair A, Vaidyanathan S, Clearie K, Williamson P, Meldrum K, Lipworth BJ. Steroid sparing effects of intranasal corticosteroids in asthma and allergic rhinitis. Allergy. 2009 Oct 5. [Epub ahead of print] PubMed PMID: 19804441.
6: Basu K, Palmer CN, Tavendale R, Lipworth BJ, Mukhopadhyay S. Adrenergic beta(2)-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol. J Allergy Clin Immunol. 2009 Dec;124(6):1188-94.e3. Epub . PubMed PMID: 19800676.
7: Clearie KL, Vaidyanathan S, Williamson PA, Goudie A, Short P, Schembri S, Lipworth BJ. Effects of chlorine and exercise on the unified airway in adolescent elite Scottish swimmers. Allergy. 2010 Feb;65(2):269-73. Epub 2009 Sep 30. PubMed PMID: 19793061.
8: Williamson PA, Clearie K, Vaidyanathan S, Lipworth B. Effects of methacholine
challenge on alveolar nitric oxide. Thorax. 2009 Jun;64(6):549-50. PubMed PMID:
19478127.
9: Nair A, Clearie K, Menzies D, Meldrum K, McFarlane L, Lipworth BJ. A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination. Pulm Pharmacol Ther. 2009 Aug;22(4):305-10. PubMed PMID: 19489129.
10: Lipworth BJ. Long-acting beta2 agonists and inhaled corticosteroids in asthma. Am J Respir Crit Care Med. 2009 May 1;179(9):853-4. PubMed PMID: 19383932.
11: Williamson PA, Menzies D, Nair A, Tutuncu A, Lipworth BJ. A proof-of-concept study to evaluate the antiinflammatory effects of a novel soluble cyclodextrin formulation of nebulized budesonide in patients with mild to moderate asthma. Ann Allergy Asthma Immunol. 2009 Feb;102(2):161-7. PubMed PMID: 19230469.
12: Nair A, Menzies D, Hopkinson P, McFarlane L, Lipworth BJ. In vivo comparison of the relative systemic bioavailability of fluticasone propionate from three anti-static spacers and a metered dose inhaler. Br J Clin Pharmacol. 2009 Feb;67(2):191-8. Epub 2009 Feb 9. PubMed PMID: 19220273; PubMed Central PMCID:
PMC2670376.
13: Vaidyanathan S, Barnes M, Lipworth BJ. Comparative safety and efficacy of 2 formulations of fluticasone aqueous nasal spray in persistent allergic rhinitis. Ann Allergy Asthma Immunol. 2009 Jan;102(1):76-83. PubMed PMID: 19205290.
14: Vaidyanathan S, Nair A, Barnes ML, Meldrum K, Lipworth BJ. Effect of levocetirizine on nasal provocation testing with adenosine monophosphate compared with allergen challenge in allergic rhinitis. Clin Exp Allergy. 2009 Mar;39(3):409-16. PubMed PMID: 19187327.
15: Lipworth BJ, Williamson PA. Beta blockers for asthma: a double-edged sword. Lancet. 2009 Jan 10;373(9658):104-5. PubMed PMID: 19135598.
16: Lipworth BJ, Clearie K. Levalbuterol kinetics. J Allergy Clin Immunol. 2009 Jan;123(1):275. PubMed PMID: 19130946.
17: McMahon AD, Lipworth BJ, Davey PG, Morris AD, Macdonald TM. Continuity of prescribing with inhaled corticosteroids and control of asthma. Pharmacoepidemiol Drug Saf. 2000 Jul;9(4):293-303. PubMed PMID: 19025832.
18: Menzies D, Jackson C, Mistry C, Houston R, Lipworth BJ. Symptoms, spirometry, exhaled nitric oxide, and asthma exacerbations in clinical practice. Ann Allergy Asthma Immunol. 2008 Sep;101(3):248-55. PubMed PMID: 18814447.
19: Vaidyanathan S, Williamson P, Lipworth BJ. Comment on: Nitric oxide evaluation in upper and lower respiratory tracts in nasal polyposis. Delclaux C, et al. Clin Exp Allergy. 2008 Oct;38(10):1697. Epub 2008 Aug 22. PubMed PMID:18727620.
20: Nair A, Menzies D, Barnes M, Burns P, McFarlane L, Lipworth BJ. Respirable dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler. Br J Clin Pharmacol. 2008 Jul;66(1):20-6. Epub 2008 Mar 13. PubMed PMID: 18341676; PubMed Central PMCID: PMC2485244.

