A. Isotope V/Q lung scan
B. PET scan of Thorax
C. High resolution CT scan thorax
D. MRI scan Thorax
E. CT pulmonary angiogram
F. Ultrasound scan of Thorax
G. Ultrasound Doppler scan of Leg
H. Contrast venogram of the leg

From the list above please select the single most appropriate imaging test to make a diagnosis in each of the following patients – assume they have already had a Chest XRay [aside from patient #3]:

1. A 50 year old, non-smoking female on HRT presents with progressive breathlessness on exertion. Her BP is 140/80, she has a left parasternal heave, and bilateral ankle oedema. He has SaO2 90%, DLCO 60%

A – The history is strongly suggestive of chronic pulmonary thromboembolic disease. V/Q scan may detect acute, and chronic unmatched deficits, to make this diagnosis. CTPA is not useful in the detection of chronic PE.

2. A 70 ear old, non-smoking man is on the orthopaedic ward following a total hip replacement. At 11 o’clock at night, he becomes acutely breathless with BP 70/50, raised JVP, centrally cyanosed, SaO2 75%, ECG shows signs of acute right heart strain

E – This man has signs compatible with a sub-massive central PE. CTPA is available out of hours, and has a very high sensitivity for central clot. An alternative approach would be to look for signs of acute right ventricular failure on Echo, as this would be sufficient evidence, in the face of the clinical picture, to consider thrombolysis.

3. A 25 year old, non-smoking woman who is 20 weeks pregnant develops acute pleuritic chest pain. She also has a swollen red tender calf, a BP of 130/80, and a pleural rub; her ECG is normal.

G – It is very likely that this lady has a DVT and a PE. Investigations to look for PE specifically involve a dose of ionising radiation, which is best avoided in pregnancy. If DVT is proven by doppler ultra sound scan, it can be assumed from the clinical history that she has a PE, and treatment will be commenced.

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About DundeeChest 3.0
Born again, phoenix from the flames of DundeeChest and DundeeChest 2.0 comes DundeeChest 3.0. The idea was to provide the medical students of Dundee University Medical School with some support for their respiratory block. Now the students have DundeeChest 4.0 for all their undergraduate needs, and now DC 3.0 is a repository for all things post-graduate. The old undergraduate material is still hidden in here, if you want it.
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